+-Associate Director / Director, Business Development & Alliance Management
Position Summary
The Associate Director/Director of Business Development and Alliance Management will be instrumental in the strategic planning and execution of key Accent partnerships, including its foundational multi-program partnership with AstraZeneca, and critical portfolio strategy and business development initiatives. This highly visible, highly collaborative role will work broadly across the organization and cross-functionally with internal and external stakeholders. Reporting to the Vice President, Head of Business Development, the Associate Director/Director of Business Development and Alliance Management will be responsible for all aspects of Alliance Management and for effectively communicating plans and partnership objectives to key stakeholders and executive management, and will be essential in contributing to key business development strategy and transactions and portfolio planning initiatives.
Responsibilities
- Execute on Business Development initiatives, including business development strategy assessments, external partner outreach, negotiation and transactions, as well as portfolio strategy initiatives, including new product strategy analyses for the Accent pipeline;
- Perform all aspects of Alliance Management, including scheduling, developing agendas, drafting minutes, actions, and follow-up; as well as manage, as needed, Joint Steering Committee and Joint Project Team activities, with oversight over partnership activity timelines, budgets, etc.;
- Develop and maintain exceptional business and scientific relationships with key internal and external stakeholders, working to gain consensus across organizations and striving to meet partnership goals and objectives;
- Leverage input from all critical organizational functions to create integrated plans for alliances that define goals, milestones, decision points, critical paths, financial assumptions and tracking, timelines, and alternative scenarios;
- Serve as a key point person for program team members on project-related communication, proactive issue identification and risk-mitigation;
- Drive process, with legal representatives, to draft or amend contracts or execute supplementary agreements, as needed, for collaborations;
- Conduct periodic partnership performance assessments with key stakeholders and implement solutions or improvements to optimize alliance performance and to maintain strong working relationships;
- Serve as an ambassador for Business Development and Alliance Management within the company
Requirements
- BS/BA in life sciences or related area (MBA/MA or PhD preferred) with five or more years of biotech and/or pharmaceutical industry experience;
- Significant understanding of the pharmaceutical research and development process and the regulatory process by which drug products are filed and approved;
- Comfort interpreting and managing deliverables under collaboration contracts;
- Excellent project management skills, including ability to coordinate cross-functional teams, meet deadlines, and manage collaborations across multiple programs and anticipate and resolve issues;
- Strong interpersonal and communication skills, including ability to clearly articulate complex issues and to engage with external parties for business development efforts;
- Excellent time management and organizational skills, demonstrating an ability to work independently, meet deadlines and prioritize work effectively;
- Ability to work effectively and congenially in a team setting with a collaborative mindset, consensus-building disposition, and culture-focus;
- Strong problem-solving, analytical skills, and excellent business judgment;
- Demonstrated self-starter mentality with a flexible approach to learning and taking on new challenges;
- Comfortable working in fast-paced, evolving, high-growth environment;
- Strong character, sense of humor, work ethic, detail-orientation, and results-driven outlook
Position: Full-Time, Exempt
Location: Lexington, MA
Accent values diversity and is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person’s race, color, gender, age, religion, national origin, ancestry, disability, marital or veteran status, genetic information, sexual orientation or any other legally protected status. Accent will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.
To apply, please send your resume to HR@accenttx.com.
Note to Third Party Staffing Agencies: Please do not forward any agency resumes. Accent Therapeutics is not responsible for any fees related to resumes that are unsolicited.
+-Director, Human Resources
Position Summary:
As a key member of the Operations team reporting to the Chief Financial Officer, the Director, Human Resources will be essential in driving HR strategy, championing employee engagement, growth and development and delivering core HR functions, including HR planning and management, recruiting and retention, organizational learning and development, compensation and benefits, performance management, employee engagement and communications, and organizational structure and design.
Responsibilities:
- Serve as a visible, involved and engaged leader to employees throughout the organization;
- Provide thought leadership on organizational and people-related strategy and execution to ensure a high-performing, engaged workforce;
- Identify, prioritize, design and implement HR programs and solutions that support employees and business objectives;
- Work with management of all levels on a variety of HR and business-related issues, both strategic and operational;
- Partner with the executive team and senior management to align the organizational structure, practices and communication with the Company’s strategy and culture;
- Provide human resources technical advice, guidance, knowledge and leadership to others within the organization;
- Lead efforts to prioritize employee engagement, growth and development in both group and 1:1 settings;
- Oversee and guide talent acquisition efforts;
- Lead organizational development efforts, including: management training, leadership development, performance review process, onboarding and interview training;
- Develop progressive and proactive compensation and benefits programs to attract prospective employees and motivate, incent, reward and retain existing employees in a manner that fosters high performance;
- Design programs to support a diverse and inclusive culture through hiring, promoting and rewards initiatives;
- Evolve HR infrastructure to a best-in-class function;
- Oversee HR related topics and initiatives for presentation to the Board of Directors and Compensation Committee
Qualifications and skills:
- Outstanding communication and listening skills;
- Demonstrated ability to build relationships and establish rapport with all levels of the organization, as well as influence positive behaviors and values throughout an organization;
- Strong background in designing and implementing organizational structures, strategic hiring and selection, employee and organizational development, compensation philosophy and total compensation programs;
- Ability to coach and counsel at all levels;
- 10+ years of progressively responsible experience in HR management, preferably in a combination of public and entrepreneurial environments;
- Experience in pharmaceutical, biotech or other life science companies is preferred
Position: Full-Time, Exempt
Location: Lexington, MA
Accent values diversity and is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person’s race, color, gender, age, religion, national origin, ancestry, disability, marital or veteran status, genetic information, sexual orientation or any other legally protected status. Accent will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.
To apply, please send your resume to HR@accenttx.com.
Note to Third Party Staffing Agencies: Please do not forward any agency resumes. Accent Therapeutics is not responsible for any fees related to resumes that are unsolicited.
+-Senior / Principal Scientist, Protein and Structural Sciences (Biophysics)
Position Summary:
As a key member of the Protein and Structural Sciences team, the Senior / Principal Scientist will play a critical and influential role in the application of biophysical methods in drug discovery. Reporting to the Director of Protein & Structural Sciences, the Senior / Principal Scientist will apply biophysical methods to understand small molecule-protein interactions and work cross-functionally with teams of internal and external scientists to utilize this expertise to provide insights that will advance Accent’s drug discovery programs.
Responsibilities:
- Design, execute, and analyze key Surface Plasmon Resonance (SPR) experiments for small molecule compound screening with a high level of independence to support hit finding, lead optimization and mechanism of inhibition studies;
- Maintain internal databases with latest results and contribute to optimization of LIMS systems for biophysical data;
- Effectively communicate biophysical information and results to a variety of audiences in multiple settings, including project teams and company management;
- Oversee activities at partner CROs producing biophysical data;
- Establish and manage an internal SPR facility at Accent
Qualifications:
- A PhD or equivalent experience in Biophysics, Biochemistry, Bioanalytical Chemistry or a closely related field;
- 4+ years of experience in industry with 2+ years laboratory experience using SPR spectroscopy, experience with Biacore platforms preferred;
- Extensive knowledge and experience with SPR and other biophysical techniques (including DSF, ITC, MST and NMR), with the ability to communicate complex information to a broad audience
- Proficiency in operating and maintaining SPR systems and associated data processing packages;
- Demonstrated commitment to innovation and scientific rigor across multiple protein targets and superfamilies;
- Ability to work in a fast-paced, team-driven environment with a collaborative and proactive attitude;
- Experience with outsourcing preferred;
- Ability to work in a fast-paced, team-driven environment with a collaborative and proactive attitude, motivated by a desire to create the novel cancer therapeutics and the vision to offer cancer patients novel therapies that extend and improve their lives
Position: Full-Time, Exempt
Location: Lexington, MA
Accent values diversity and is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person’s race, color, gender, age, religion, national origin, ancestry, disability, marital or veteran status, genetic information, sexual orientation or any other legally protected status. Accent will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.
To apply, please send your resume to HR@accenttx.com.
Note to Third Party Staffing Agencies: Please do not forward any agency resumes. Accent Therapeutics is not responsible for any fees related to resumes that are unsolicited.
+-Scientist, Lead Discovery
Position Summary:
As a key member of the Lead Discovery team, reporting to the Head of Lead Discovery, the Scientist, Lead Discovery will develop and implement biochemical assays for internal and external use and collaborate with a cross-functional team of scientists within the company and with external partners to support drug discovery efforts across the Accent portfolio.
Responsibilities:
- Design and execution of biochemical assays for multiple novel target classes for use in screening and characterizing small molecule inhibitors;
- Analyze data, including curve fitting and IC50 calculations using state-of-the art graphing software, and documentation of data and results using electronic laboratory notebooks;
- Operate and maintain laboratory equipment such as multimodal microplate readers, microplate washers and liquid handlers of varying capacity;
- Develop processes for storage, retrieval and assay-ready plating workflows for Accent chemical matter;
- Perform lab-based research with minimal supervision in a collaborative, fast-paced and dynamic environment;
- Independently summarize, analyze and present your work to project and senior leadership teams
Qualifications and skills:
- BA/BS in Biochemistry, Enzymology or related field plus a minimum of 6 years of industry experience or the equivalent expertise;
- Knowledge of enzymology, enzyme kinetics and current assay approaches for several enzymatic classes and protein-protein-interaction screening formats;
- Familiarity with current plate readers, liquid handlers and other tools to execute assay development and routine screening;
- Experience in state-of-the-art data visualization, graphing and curve fitting software;
- Knowledge of research informatics inventory and assay databases;
- Strong attention to detail and the ability to multi-task required;
- Familiarity with high throughput screening using multiple techniques (enzymatic assays, binding assays (ie, DEL, ASMS)) and hit validation preferred;
- Experience with outsourcing preferred
Position: Full-Time, Exempt
Location: Lexington, MA
Accent values diversity and is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person’s race, color, gender, age, religion, national origin, ancestry, disability, marital or veteran status, genetic information, sexual orientation or any other legally protected status. Accent will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.
To apply, please send your resume to HR@accenttx.com.
Note to Third Party Staffing Agencies: Please do not forward any agency resumes. Accent Therapeutics is not responsible for any fees related to resumes that are unsolicited.
+-Senior / Principal Scientist, Biology
Position Summary:
As a key member of the Biology team, the Senior/Principal Scientist, Biology will join a dynamic, enthusiastic, highly interdisciplinary, and collaborative team to elucidate the role of RNA modification in human disease and progress the Accent pipeline.
Responsibilities:
- Serve as a key member of a cross-functional project team working with biochemists, biologists, chemists, protein scientists, DMPK and Accent leadership to progress programs through candidate selection and IND enabling studies;
- Independently design and execute experiments critical to the advancement of our pipeline;
- Proactively review literature to bring in newest scientific findings, ideas, and methods/technologies for discovery research; and
- Interpret, summarize and present research findings in internal and external scientific meetings/conferences.
Qualifications:
- A PhD in Molecular Biology, Cancer Biology, or a related field plus a minimum of 5-10 years of industry experience and a proven track record of productivity and creativity;
- Project or program leadership experience in the biotech/pharmaceutical industry preferred;
- Extensive experience in mammalian tissue culture (including si/shRNA, CRISPR, and lentivirus) and modern molecular biology techniques (Western blotting, RT-qPCR);
- Broad knowledge of cancer biology and related signaling-pathways;
- Capability to work within a dynamic matrix environment, with strong contribution to project strategies and progression;
- Excellent organizational and communication skills;
- Experience working with and managing in vitro and in vivo biology projects at CROs.
Position: Full-Time, Exempt
Location: Lexington, MA
Accent values diversity and is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person’s race, color, gender, age, religion, national origin, ancestry, disability, marital or veteran status, genetic information, sexual orientation or any other legally protected status. Accent will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.
To apply, please send your resume to HR@accenttx.com.
Note to Third Party Staffing Agencies: Please do not forward any agency resumes. Accent Therapeutics is not responsible for any fees related to resumes that are unsolicited.
